All functions |
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Biphasic antibody boosting-waning model |
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Biphasic antibody boosting-waning model Rcpp implementation |
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Biphasic antibody boosting-waning model with cross-reactive strains |
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Monophasic antibody boosting-waning model |
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Monophasic antibody boosting-waning model Rcpp implementation |
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Monophasic antibody boosting-waning model with cross-reactive strains |
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Power law antibody boosting and waning |
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Function to calculate the risk of infection at a given biomarker quantity |
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Convert 2D indexing to 1D indexing |
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Draw parameters with fixed effects |
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Draw parameters fixed effects with biomarker-quantity-dependent boosting |
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Draw parameters with random effects |
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Draw parameters random effects with biomarker-quantity-dependent boosting |
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Example biomarker map |
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Example numeric biomarker map |
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Example biomarker states |
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Example biomarker states (wide) |
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Example demography tibble |
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Example force of exposure |
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Example exposure probability |
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Example force of exposure parameters ( |
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Example imune histories |
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Example immune histories (wide) |
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Example model parameters ( |
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Example model parameters for biphasic waning model |
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Example numeric model parameters ( |
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Example model parameters for typhoid model ( |
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Example observed biomarker states |
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Exposure Model Modified By Relevant Demographic Elements |
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Fixed probability of exposure |
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Gaussian process model |
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Known individual-level probability of exposure |
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Exposure Model Simple- Force of Exposure (FOE) |
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SIR Exposure Model |
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Generate population demography dataset |
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Null immunity model |
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Immunity model for infection with biomarker-quantity-mediated protection |
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Immunity model for vaccination and infection events with biomarker-quantity-mediated protection |
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Simple immunity model for vaccination and infection events |
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Vaccine-mediated immunity model |
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Convert normal distributions to log-normal distributions and return mean |
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Convert normal distributions to log-normal distributions and return standard deviation |
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Observation model for continuous assays with no added noise |
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Observation model for continuous assays with detection limits and no added noise |
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Observation model for continuous assays with detection limits and added noise |
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Observation model for continuous assays with no detection limits and added noise |
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Observation model for discrete assays with no added noise |
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Observation Model For Discrete Assays With Added Noise |
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Plots example trajectories of the provided antibody kinetics model |
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Generate a plot displaying proportion of full boost received at each starting biomarker quantity |
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Plot biomarker mediated protection graphs for each pathogen |
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Plot biomarker quantities across time for all individuals and biomarkers |
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Plot individual exposure probabilities across time for all individuals and exposure events |
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Plots the probability of exposure over time for the provided exposure models |
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Plot probability of a successful exposure event for all individuals and exposure events |
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Plot individual immune histories |
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Plot Observed Biomarker Quantities For One Observation Time |
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Plot biomarker quantities for multiple observation times and paired samples |
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Plot biomarker states and immune histories for a subset of individuals |
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Pre-compute exposure probabilities |
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Reformat |
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Main simulation function for serosim |
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Simulate random birth times |
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Simulate incidence curve using Gaussian Process |
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Simulate removal times for individuals |
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runserosim function update message |